Part 3 of Owen’s treatise
The Holy Spirit is the agent in mortification (Rom.8:13): He it is who takes away of the stony heart, Ezek. 11:19, 36:26, “I will give my Spirit, and take away the stony heart;” “Without Christ we can do nothing,” John 15:5. All actings of any grace whatever, from him, are by the Spirit, by whom he alone works in and upon believers. As per Acts 5:31 he grants repentance of which mortification is no small portion. Having “received the promise of the Holy Ghost,” he sends him abroad for that end, Acts 2:33.
All self-denying religious acts, like many indulged in by Romanists, Hindu monks and fanatical Muslims are useless and impotent in mortification because NOT in the Bible.